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MME anticorps (CF®568)

L’anticorps Souris Monoclonal anti-MME a été validé pour FACS et IF. Il convient pour détecter MME dans des échantillons de Humain.
N° du produit ABIN7656842

Aperçu rapide pour MME anticorps (CF®568) (ABIN7656842)

Antigène

Voir toutes MME Anticorps
MME (Membrane Metallo-Endopeptidase (MME))

Reactivité

  • 243
  • 45
  • 39
  • 3
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  • 2
  • 2
  • 2
  • 2
  • 1
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Humain

Hôte

  • 153
  • 96
  • 2
  • 1
Souris

Clonalité

  • 167
  • 84
  • 2
Monoclonal

Conjugué

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  • 1
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Cet anticorp MME est conjugé à/à la CF®568

Application

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Flow Cytometry (FACS), Immunofluorescence (IF)

Clone

MME-1620
  • Fonction

    CD10 (Membrane Metalloendopeptidase)(MME/1620), CF568 conjugate

    Attributs du produit

    CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA)) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant full-length human CD10 protein (MME)

    Isotype

    IgG1, kappa
  • Indications d'application

    Flow cytometry: 1-2 μg/million cells, Western blot 0.5-1 μg/mL, Immunofluorescence: 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

    Commentaires

    Positive Control: Ramos cells (FACS/IF). Jurkat or LnCap lysates (WB). Kidney (IHC).

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    MME (Membrane Metallo-Endopeptidase (MME))

    Autre désignation

    CD10

    Sujet

    Synonyms: CD10, Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen (CALLA), Enkephalinase, gp100, Membrane metalloendopeptidase, Neutral endopeptidase

    Gene Symbol: MME

    Tissue Expression: B-cells|Epithelial cells

    Poids moléculaire

    100 kDa

    ID gène

    4311

    UniProt

    P08473

    Pathways

    Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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